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your search for "Bei Liu" returned 74 result(s).

• Birth of Parthenote Mice Directly from Parthenogenetic Embryonic Stem Cells

• Published on Jun 19, 2009

Abstract Mammalian parthenogenetic embryos are not viable and die because of defects in placental development and genomic imprinting. Parthenogenetic ESCs (pESCs) derived from parthenogenetic embryos might advance regenerative medicine by avoiding immuno‐rejection. However, previous reports suggest that pESCs may fail to differentiate and contribute to some organs in chimeras, including muscle and pancreas, and it remains unclear...

• Characteristics of proliferation and differentiation of spleen colony‐forming cells from bone marrow

• Published on Jan 01, 1996

Abstract By using c‐band staining or sex chromosome identification techniques, we have demonstrated that some of the spleen colony‐forming cells from normal bone marrow have the potential to form both myeloid and lymphoid elements.

• A Role for Borg5 During Trophectoderm Differentiation

• Published on Apr 15, 2010

Abstract Stem cell differentiation is accompanied by a gradual cellular morphogenesis and transcriptional changes. Identification of morphological regulators that control cell behavior during differentiation could shed light on how cell morphogenesis is coupled to transcriptional changes during development. By analyzing cellular behavior during differentiation of mouse embryonic stem cells (ESCs), we uncover a role of Borg5 (binder...

• Efficient Production of Mice from Embryonic Stem Cells Injected into Four‐ or Eight‐Cell Embryos by Piezo Micromanipulation

• Published on May 08, 2008

Abstract The conventional method for producing embryonic stem (ES) cell‐derived knockout or transgenic mice involves injection of ES cells into normal, diploid blastocysts followed by several rounds of breeding of resultant chimeras and thus is a time‐consuming and inefficient procedure. F0 ES cell pups can also be derived directly from tetraploid embryo complementation, which requires fusion of two‐cell embryos. Recently, F0 ES...

• Human Embryonic Stem Cells Have Enhanced Repair of Multiple Forms of DNA Damage

• Published on Jun 19, 2008

Abstract Embryonic stem cells need to maintain genomic integrity so that they can retain the ability to differentiate into multiple cell types without propagating DNA errors. Previous studies have suggested that mechanisms of genome surveillance, including DNA repair, are superior in mouse embryonic stem cells compared with various differentiated murine cells. Using single‐cell gel electrophoresis (comet assay) we found that human...