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your search for "Bei Liu" returned 74 result(s).

Abstract Bone marrow contains a population of rare progenitor cells capable of differentiating into osteoblasts, chondrocytes, adipocytes, myoblasts, and hematopoiesis‐supporting stromal cells. These cells, referred to as mesenchymal progenitor cells (MPCs), can be purified and culture‐expanded from animals and humans. Using bone‐marrow‐conditioned medium combined with basic fibroblast growth factor, we cultured a relatively...

Abstract Periodontitis is one of the most widespread infectious diseases in humans. It is the main cause of tooth loss and associated with a number of systemic diseases. Until now, there is no appropriate method for functional periodontal tissue regeneration. Here we establish a novel approach of using allogeneic periodontal ligament stem cells (PDLSCs) sheet to curing periodontitis in a miniature pig periodontitis model....

Abstract Hematopoietic stem cells (HSCs) can remain quiescent or they can enter the cell cycle, and either self‐renew or differentiate. Although cyclin C and cyclin dependent kinase (cdk3) are essential for the transition from the G0 to the G1 phase of the cell cycle in human fibroblasts, the role of cyclin C in hematopoietic stem/progenitor cells (HSPCs) is not clear. We have identified an important role of cyclin C (CCNC) in regulating human...

Abstract The Foxd3 forkhead transcription factor is required for maintaining pluripotent cells in the early mouse embryo and for the establishment of murine embryonic stem cell (ESC) lines. To begin to understand the role of Foxd3 in ESC maintenance, we derived ESC lines from blastocysts that carried two conditional Foxd3 alleles and a tamoxifen‐inducible Cre transgene. Tamoxifen treatment produced a rapid and near complete loss of...

Abstract Using a single spleen colony transplantation technique and sex chromosome typing as a natural cytogenetic marker, most spleen colony‐forming cells (CFC) in adult bone marrow or fetal livers of inbred LACA or C57 mice re‐established hemopoiesis in lethally irradiated mice when the spleen colonies were sampled at 13 days after transplantation. However, most of the spleen colony‐forming cells in the peripheral blood of normal...

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