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your search for "Bei Liu" returned 74 result(s).

Abstract Over 80 human T helper cell (Th) clones reactive with human cytomegalovirus (HCMV) were generated using purified whole Towne strain HCMV as the in vitro antigen. These cloned T cells are CD3+, CD4+, CD8‐ and proliferate specifically to HCMV. All of the clones tested produce interleukin 2 and gamma‐interferon and failed to show HCMV‐specific cytotoxicity or natural killer (NK) activity. Most of the Th clones recognize multiple...

Abstract Direct‐current electrical fields (EFs) promote nerve growth and axon regeneration. We report here that at physiological strengths, EFs guide the migration of neuronal stem/progenitor cells (NSPCs) toward the cathode. EF‐directed NSPC migration requires activation of N‐methyl‐d‐aspartate receptors (NMDARs), which leads to an increased physical association of Rho GTPase Rac1‐associated signals to the membrane NMDARs and the...

Abstract Peripheral blood– derived endothelial progenitor cells (EPCs) have considerable potential for the autologous therapy of vascular lesions or ischemic tissues. By introducing stable genetic modifications into these cells, this potential might be further enhanced. We investigated to what extent transgene expression can be controlled by using different transgene promoters. This was investigated in early‐ or late‐outgrowth human...

Abstract Periodontitis is a periodontal tissue infectious disease and the most common cause for tooth loss in adults. It has been linked to many systemic disorders, such as coronary artery disease, stroke, and diabetes. At present, there is no ideal therapeutic approach to cure periodontitis and achieve optimal periodontal tissue regeneration. In this study, we explored the potential of using autologous periodontal ligament stem...

Abstract Heterotopic ossification (HO), the abnormal formation of true marrow‐containing bone within extraskeletal soft tissues, is a serious bony disorder that may be either acquired or hereditary. We utilized an animal model of the genetic disorder fibrodysplasia ossificans progressiva to examine the cellular mechanisms underlying HO. We found that HO in these animals was triggered by soft tissue injuries and that the effects were...

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